2'-5'-寡腺苷酸合成酶3抗体
规格：1mg/1ml
英文名： OAS3
别名： (2-5'')oligo(A) synthase 3; 2 5' oligo(A) synthetase 3; 2 5'LIGO; 2 5A synthetase 3; 2''-5''-oligoadenylate synthase 3; 2-5A synthase 3; MGC133260; OAS3 2' 5' oligoadenylate synthetase 3, 100kDa; OAS3
分子量： 121kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OAS3
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
2'-5'-寡腺苷酸合成酶3抗体产品介绍：background: The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100,2'-5'-寡腺苷酸合成酶3抗体 contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2 Function: May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2'-5'-寡腺苷酸合成酶3抗体2',5'-oligoadenylate molecules. GTP can be an alternative substrate. Tissue Specificity: Present at high level in placenta trophoblast. Similarity: Belongs to the 2-5A synthase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
2'-5'-寡腺苷酸合成酶3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid