14-3-3 α + β蛋白抗体
规格：1mg/1ml
英文名： 14-3-3 alpha + beta
别名： 14 3 3 alpha; 14 3 3 protein beta/alpha; 14-3-3 protein beta/alpha; 1433B_HUMAN; Brain protein 14 3 3 beta isoform; GW128; HS 1; KCIP-1; KCIP1; N-terminally processed; Protein 1054; Protein kinase C i
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human 14-3-3 a
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：细胞浆 细胞膜
14-3-3 α + β蛋白抗体产品介绍：background: 14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family. Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the14-3-3 α + β蛋白抗体 modulation of the activity of the binding partner. Negative regulator of osteogenesis. Subcellular Location: Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Post-translational modifications: The alpha, brain-specific form differs from the beta form in being phosphorylated. Isoform Short contains a N-acetylmethionine at position 1. Similarity: Belongs to14-3-3 α + β蛋白抗体 the 14-3-3 family. Gene ID: 7529 Database links: Entrez Gene: 7529 Human Entrez Gene: 56011 Rat Omim: 601289 Human SwissProt: P31946 Human SwissProt: P35213 Rat Unigene: 643544 Human Unigene: 8653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
14-3-3 α + β蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞凋亡
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid