硫氧还蛋白还原酶抗体
规格:1mg/1ml
英文名: Peroxiredoxin 4
别名: 2 Cys Peroxiredoxin; ACR 1; ACR1; Alu co repressor 1; Alu co-repressor 1; Alu corepressor 1; Antioxidant enzyme; Antioxidant enzyme B166; AOEB 166; AOEB166; B166; Liver tissue 2D page spot 71B; MGC117
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human 2 Cys Pe
交叉反应:Human, Mouse, Rat, Pig, Horse,
细胞定位:细胞浆 细胞膜
硫氧还蛋白还原酶抗体产品介绍:background: Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are involved in cell proliferation, differentiation, and apoptosis. There are many isoforms(about 50 proteins), known on the basis of amino acid sequence homology, particularly the amino-terminal region containing an active site cysteine residue. The thiol-specific antioxidant activity is distributed throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes share the thioredoxin 硫氧还蛋白还原酶抗体dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kilodaltons in molecular size and vary in subcellular localization:PrxI, II and VI in cytosol, PrxIII in mitochondria, PrxIV in ER and secretion, PrxV showing complicated distribution including peroxisome, mitochondria and cytosol. Subcellular Location: Cytoplasmic and Mitochondrial Gene ID: 10549 Database links: Entrez Gene: 10549 Human Entrez Gene: 10935 Human Entrez Gene: 5052 Human Entrez Gene: 硫氧还蛋白还原酶抗体7001 Human Entrez Gene: 113898 Rat SwissProt: P30044 Human SwissProt: P30048 Human SwissProt: P32119 Human SwissProt: Q06830 Human SwissProt: Q13162 Human SwissProt: Q9R063 Rat Unigene: 502823 Human Unigene: 2944 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硫氧还蛋白还原酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞凋亡
储存条件:
来源: Rabbit
外观: Lyophilized or Liquid