DNA拓普西异构酶Topo IIIα抗体
规格：1mg/1ml
英文名： Topoisomerase III
别名： DNA topoisomerase 3 alpha; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; TOP 3; TOP3; TOP3A; TOP3A_HUMAN; topoisomerase (DNA) III alpha; topoisomerase (DNA) III; topoisomerase III alpha.
分子量： 112kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Topoisom
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
DNA拓普西异构酶Topo IIIα抗体产品介绍：background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008] Function:DNA拓普西异构酶Topo IIIα抗体Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Tissue Specificity: High expression is found in testis, heart, skeletal muscle and pancreas. Similarity: Belongs to the prokaryotic type I/IIIDNA拓普西异构酶Topo IIIα抗体 topoisomerase family. Contains 1 Toprim domain. Gene ID: 7156 Database links: Entrez Gene: 7156 Human Omim: 601243 Human SwissProt: Q13472 Human Unigene: 592115 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA拓普西异构酶Topo IIIα抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid