锌指蛋白139抗体
规格:1mg/1ml
英文名: ZNF139
别名: 9130423L19Rik; KOX18; MGC138429; MGC63357; OTTHUMP; PHZ 37; PHZ-37; Zinc finger protein 139; Zinc finger protein 36 (KOX 18); Zinc finger protein 36; Zinc finger protein KOX18; Zinc finger
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF139
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
锌指蛋白139抗体产品介绍:background: The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91锌指蛋白139抗体 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010] Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 6 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 锌指蛋白139抗体1 SCAN box domain. Database links: Entrez Gene: 7586 Human Entrez Gene: 74570 Mouse Entrez Gene: 498160 Rat Omim: 601260 Human SwissProt: P17029 Human SwissProt: Q8BGS3 Mouse SwissProt: Q4KLI1 Rat Unigene: 615360 Human Unigene: 213114 Mouse Unigene: 113295 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白139抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 锌指蛋白 表观遗传学
储存条件:
来源: Rabbit
外观: Lyophilized or Liquid