锌指蛋白170抗体
规格:1mg/1ml
英文名: ZNF170
别名: Putative LAG1 interacting protein; Ring finger protein 170。
分子量: 30kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF170
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Guinea Pig, Cat,
细胞定位:细胞膜
锌指蛋白170抗体产品介绍:background: This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia.锌指蛋白170抗体 Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Function: The ring finger is a specialized type of zinc finger of 40 to 60 residues that binds two atoms of zinc and mediates protein-protein interactions. There are five known isoforms of RNF170. Subcellular Location: Membrane; Multi pass membrane protein. Database links: Entrez Gene: 427296 Chicken Entrez Gene: 锌指蛋白170抗体617379 Cow Entrez Gene: 475568 Dog Entrez Gene: 81790 Human Entrez Gene: 77733 Mouse Entrez Gene: 364654 Rat SwissProt: Q96K19 Human SwissProt: Q8CBG9 Mouse Unigene: 696153 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白170抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 锌指蛋白 表观遗传学 泛素
储存条件:
来源: Rabbit
外观: Lyophilized or Liquid