锌指蛋白141抗体
规格：1mg/1ml
英文名： ZNF141
别名： D4S90; PAPA6; pHZ-44; Zinc finger protein 141.
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF141
交叉反应：Human,
细胞定位：细胞核
锌指蛋白141抗体产品介绍：background: A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders. Function: May be involved in transcriptional regulation as a repressor. Plays a role in limb development. Subcellular Location: Nuclear. DISEASE: The disease is caused by mutations affecting the gene锌指蛋白141抗体 represented in this entry. Disease description:A condition characterized by the occurrence of supernumerary digits in the upper and/or lower extremities. In postaxial polydactyly type A, the extra digit is well-formed and articulates with the fifth or a sixth metacarpal/metatarsal. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 11 C2H2-type zinc fingers. Contains 1 KRAB domain.锌指蛋白141抗体 Database links: Entrez Gene: 7700 Human Omim: 194648 Human SwissProt: Q15928 Human Unigene: 654355 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白141抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid