蓖麻**B链抗体
规格：1mg/1ml
英文名： Ricin B chain
别名： Ricin toxin B chain; RCA 60; Ricin B lectin; Ricin chain B; Ricin precursor; rRNA N-glycosidase; RT B; RTB.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Ricin B
交叉反应：Reacts with Ricinus communis (Castor Bean plant).
细胞定位：
蓖麻**B链抗体产品介绍：Function: Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the蓖麻**B链抗体 entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity). Subunit: Disulfide-linked dimer of A and B chains.The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).蓖麻**B链抗体 Gene ID: 8287993 Database links: Entrez Gene: 8287993 Ricinus communis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蓖麻**B链抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid