旋转异构酶FKBP6抗体
规格：1mg/1ml
英文名： FKBP6
别名： 36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; EC 5.2.1.8; FK506 binding protein 6; FK506-binding protein 6; FKBP 36; FKBP-36; FKBP-6; FKBP36; fkbp6; FKBP6_HUMAN; Immunophili
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-17F
旋转异构酶FKBP6抗体交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
产品介绍：background: FKBP6 is a 327 amino acid protein that, like other PPIases, accelerate the folding of proteins. As a component in synaptonemal complexes, FKBP6 is involved in homologous chromosomes pairing and male infertility in mice. There has been some suggestion that FKBP6 may play a role in modifying the susceptibility to idiopathic spermatogenic impairment in humans. Ubiquitously expressed in all tissues, FKBP6 is present at highest levels in testis, liver, kidney, skeletal muscle and heart. The gene encoding FKBP6 maps within a region of human chromosome 7 that has been implicated in Williams-Beuren syndrome, a rare developmental disorder involving abnormalities of the cardiovascular and musculoskeletal systems. Hemizygous deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren旋转异构酶FKBP6抗体syndrome. Function: PPIases accelerate the folding of proteins. Tissue Specificity: Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney. DISEASE: Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal旋转异构酶FKBP6抗体 crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. Similarity: Contains 1 PPIase FKBP-type domain. Contains 3 TPR repeats. Database links: UniProtKB/Swiss-Prot: O75344.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产旋转异构酶FKBP6抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 发育生物学 生长因子和** t-**细胞
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid