Bax相互作用因子1抗体
规格：1mg/1ml
英文名： Bif
别名： Bax interacting factor 1; Bax-interacting factor 1; Bif 1; Bif-1; CGI 61; Endophilin B1; Endophilin-B1; SH3 domain GRB2 like endophilin B1; SH3 domain-containing GRB2-like protein B1; Sh3glb1; SH3p13;
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Bif
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆 细胞膜
Bax相互作用因子1抗体产品介绍：background: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes. Function: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. Subunit: Binds DNM1, HTT, AMPH, BIN1 and ARFGAP1 (By similarity). Homodimer, and heterodimer with SH3GLB2. BindsBax相互作用因子1抗体 BAX. Induction of apoptosis augments BAX binding. Subcellular Location: Cytoplasm. Golgi apparatus membrane. Mitochondrion outer membrane. Association with the Golgi apparatus depends on the cell type. Tissue Specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes. Bax相互作用因子1抗体Post-translational modifications: Phosphorylated at Thr-145 by CDK5; this phosphorylation is required for autophagy induction in starved neurons and facilitates homodimerization. Similarity: Belongs to the endophilin family. Contains 1 BAR domain. Contains 1 SH3 domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Bax相互作用因子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid