核仁蛋白3抗体
规格：1mg/1ml
英文名： Nucleolar protein 3
别名： Apoptosis repressor with CARD; ARC; Muscle enriched cytoplasmic protein; MYC; Myp; NOP; Nop30; Nucleolar protein 3 (apoptosis repressor with CARD domain); Nucleolar protein 3; Nucleolar protein of 30
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse Nucleola
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞核 细胞浆
产品介绍：background: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase 核仁蛋白3抗体family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis. Function: May be核仁蛋白3抗体 involved in RNA splicing (By similarity). Subunit: Interacts with SFRS9/SRp30c, NPM1, CASP2, CASP8 and TFPT (By similarity). Subcellular Location: Cytoplasm and Nucleus > nucleolus. Similarity: Contains 1 CARD domain. Gene ID: 78688 Database links: Entrez Gene:核仁蛋白3抗体 8996 Human Entrez Gene: 78688 Mouse Entrez Gene: 85383 Rat Omim: 605235 Human SwissProt: O60936 Human SwissProt: Q9D1X0 Mouse SwissProt: Q62881 Rat Unigene: 513667 Human Unigene: 204876 Mouse Unigene: 475715 Mouse Unigene: 86956 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核仁蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 细胞凋亡
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid