BCL10结合蛋白和激活核转录因子抗体
规格：1mg/1ml
英文名： CARD10
别名： Bcl10 binding protein and activator of NFKB; BIMP1; CAR10_HUMAN; CARD 10; CARD-containing MAGUK 3; CARD-containing MAGUK protein 3; CARD10; Carma 3; CARMA3; Caspase Recruitment Domain family member 10
分子量： 116kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CARD10
交叉反应：Human, Mouse, Rat, Dog, Monkey,
细胞定位：
BCL10结合蛋白和激活核转录因子抗体产品介绍：background: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family, including the caspase recruitment domain (CARD) protein family with the exception of CARD9. The CARD domain consists of 6 or 7 antiparallel alpha helices. CARD family members participate in apoptosis signaling through highly specific protein-protein homophilic interactions. CARD 10 (also designated CARD-containing BCL10结合蛋白和激活核转录因子抗体MAGUK protein 3 or Carma 3) interacts with BCL-10 to activate NFⅹB. CARD10 is expressed in a variety of ***** and fetal tissues, including heart, kidney and liver, and in multiple cancer cell lines. Function: Activates NF-kappa-B via BCL10 and IKK. Tissue Specificity: Detected in ***** heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidneyBCL10结合蛋白和激活核转录因子抗体. Similarity: Contains 1 CARD domain. Gene ID: 607209 Database links: Entrez Gene: 29775 Human Entrez Gene: 105844 Mouse Omim: 607209 Human SwissProt: Q9BWT7 Human SwissProt: P58660 Mouse Unigene: 57973 Human Unigene: 17629 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产BCL10结合蛋白和激活核转录因子抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid