凋亡加强结构域蛋白8抗体
规格：1mg/1ml
英文名： CARD8
别名： Apoptotic protein NDPP 1; Apoptotic protein NDPP1; CARD 8; CARD inhibitor of NF kappa B activating ligand; CARD inhibitor of NF kappaB activating ligand; CARD inhibitor of NF kappaB activating ligands
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CARD8
交叉反应：Human,
细胞定位：细胞核 细胞浆
凋亡加强结构域蛋白8抗体产品介绍：background: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases. Function: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function 凋亡加强结构域蛋白8抗体would be the activation of proinflammatory caspases. [SUBUNIT] May form homodimers. Interacts with NEMO and DRAL. Binds to caspase-1, CARD16/pseudo-ICE and CARD18/ICEBERG. Interacts with FNBP3 (By similarity). Interacts with NALP2 NACHT domain. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: High expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow. Similarity: Contains 1 CARD domain. Gene ID: 22900 Database links:凋亡加强结构域蛋白8抗体 Entrez Gene: 22900 Human Omim: 609051 Human SwissProt: Q9Y2G2 Human Unigene: 446146 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凋亡加强结构域蛋白8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid