FAS凋亡抑制分子1抗体
规格：1mg/1ml
英文名： FAIM1
别名： FAIM 1; FAIM; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule; FAIM1_HUMAN.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAIM1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Zebrafish
细胞定位：细胞浆
FAS凋亡抑制分子1抗体产品介绍：background: FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology. Function: Plays a role as an inducible effector molecule that mediates FAS凋亡抑制分子1抗体Fas resistance produced by surface Ig engagement in B cells (By similarity). Subcellular Location: Cytoplasm (By similarity). Similarity: Belongs to the FAIM1 family. Gene ID: 55179 Database links: Entrez Gene: 55179 Human Entrez Gene: 23873 Mouse Entrez Gene: 100362113 Rat Entrez Gene: 140930 Rat SwissProt: Q9NVQ4 Human SwissProt: Q9WUD8 Mouse SwissProt: Q8R5H8 Rat Unigene:FAS凋亡抑制分子1抗体 173438 Human Unigene: 74605 Mouse Unigene: 106419 Rat Unigene: 199757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAS凋亡抑制分子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid