双特异性磷酸酶22抗体
规格:1mg/1ml
英文名: DUSP22
别名: Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DUSP22/J
交叉反应:Human, Mouse, Rat, Cow, Rabbit,
细胞定位:细胞核 细胞浆
双特异性磷酸酶22抗体产品介绍:background: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK) Function: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity). Subunit: Monomer. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.双特异性磷酸酶22抗体 Post-translational modifications: Myristoylation regulates subcellular location, and is necessary for activation of JNK. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. Gene ID: 56940 Database links: Entrez Gene: 56940 Human Entrez Gene: 105352 Mouse Entrez Gene: 361242 Rat SwissProt:双特异性磷酸酶22抗体 Q9NRW4 Human SwissProt: Q99N11 Mouse Unigene: 29106 Human Unigene: 289646 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双特异性磷酸酶22抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞凋亡 细胞周期蛋白 转录调节因子 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid