间充质同源盒蛋白2抗体
规格：1mg/1ml
英文名： MEOX 2
别名： GAX; Growth arrest-specific homeobox; Homeobox protein MOX 2; Homeobox protein MOX-2; meox2; MEOX2_HUMAN; Mesenchyme homeobox 2; MOX2.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MEOX 2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
间充质同源盒蛋白2抗体产品介绍：background: Closely related homeobox proteins, MOX-1 and MOX-2, belong to a family of nonclustered, diverged homeobox genes that are expressed in overlapping patterns in the paraxial mesoderm and its derivatives. MOX-1 and MOX-2 function transiently in the formation of mesodermal and mesenchymal derivatives. MOX-1 and MOX-2 are implicated in the early steps of mesoderm formation during gastrulation. In addition, the MOX proteins are also involved in somatic differentiation. Significantly, MOX-1 associates more strongly with Pax-1, whereas MOX-2 preferentially associates with Pax-3. Specifically, expression of MOX-2 (also known as mesenchyme homeobox 2 or GAX), has been shown to be critical in axial skeleton development. MOX-2 is not needed for the migration of myogenic precursors间充质同源盒蛋白2抗体 into the limb bud, but it is essential for normal appendicular muscle formation and for the normal regulation of myogenic genes. MOX-2 is expressed in placental tissue. The human MEOX2 gene maps to chromosome 7p21.1 and encodes the MOX-2 protein. Mutations in the gene may be involved in craniofacial and/or skeletal abnormalities. Function: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell 间充质同源盒蛋白2抗体cycle. Subunit: Interacts with RNF10. Subcellular Location: Nucleus. Tissue Specificity: Embryo and placenta. Similarity: Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: P50222.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产间充质同源盒蛋白2抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 神经生物学 信号转导 细胞因子 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid