酪氨酸蛋白激酶受体A6抗体
规格：1mg/1ml
英文名： EphA6
别名： Ehk 2; Ehk2; EPH homology kinase 2; Eph Receptor A6; EphA6; ephrin receptor EphA6; ephrin type A receptor 6; Hek12; EPHA6_HUMAN.
分子量： 114kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EphA6/Ep
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
酪氨酸蛋白激酶受体A6抗体产品介绍：background: The Eph family of receptors comprises the largest known family of receptor tyrosine kinases. Ligands of Eph family receptors are structurally related membrane bound proteins that can be subdivided into two major subclasses, ephrin A and ephrin B. Expression of Eph receptors is tissue specific and appears to be tied to developmental events. Ligands in the ephrin A subclass, including the prototype family member ephrin A1 (B61), are membrane associated through glycosylphosphatidyl inositol linkages, whereas ephrin B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction. Function: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading酪氨酸蛋白激酶受体A6抗体 to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). Subunit: Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein (By similarity).酪氨酸蛋白激酶受体A6抗体 Tissue Specificity: Expressed in brain and testis. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain. Database links: UniProtKB/Swiss-Prot: Q9UF33.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酪氨酸蛋白激酶受体A6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 神经生物学 信号转导 激酶和磷酸酶 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid