血管生成素相关蛋白5
规格：1mg/1ml
英文名： ANGPTL5
别名： Angiopoietin like 5; Angiopoietin related protein 5; Angiopoietin-like protein 5; Angiopoietin-related protein 5; ANGL5_HUMAN; ANGPTL 5; ANGPTL5; Fibrinogen like; hide
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ANGPTL5
交叉反应：Human, Chicken, Pig, Horse, Sheep,
血管生成素相关蛋白5细胞定位：分泌型蛋白
产品介绍：background: Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in ***** heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the血管生成素相关蛋白5WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Subcellular Location: Secreted (Potential). 血管生成素相关蛋白5Tissue Specificity: Mainly expressed in ***** heart. Similarity: Contains 1 fibrinogen C-terminal domain. Gene ID: 253935 Database links: Entrez Gene: 253935 Human Omim: 607666 Human SwissProt: Q86XS5 Human Unigene: 318370 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产血管生成素相关蛋白5品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid