结肠癌抗原8抗体
规格:1mg/1ml
英文名: SDCCAG8
别名: Antigen NY CO 8; CCCAP; Centrosomal colon cancer autoantigen protein; HSPC085; NPHP10 gene; NY-CO-8; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog;
分子量: 83 kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SDCCAG8
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
结肠癌抗原8抗体产品介绍:background: The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. Function: Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis. Subunit: Homodimer (By similarity). Interacts with OFD1; the interaction is direct. Interacts with FAM161A. Subcellular Location: Isoform 2: Cytoplasm. Tissue Specificity: Expressed in thymus结肠癌抗原8抗体, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. DISEASE: Defects in SDCCAG8 are the cause of Senior-Loken syndrome type 7 (SLSN7) [MIM:613615]. SLSN7 is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes 结肠癌抗原8抗体apparent during the first year of life. Database links: UniProtKB/Swiss-Prot: Q86SQ7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
结肠癌抗原8抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞类型标志物 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid