多瘤病毒增强了结合蛋白2β抗体
规格:1mg/1ml
英文名: PEBP2B
别名: CBF b; CBF beta; CBF-beta; CBFB; CBFbeta; Core binding factor beta subunit; core binding factor subunit beta; Core-binding factor subunit beta; PEA 2; PEA2; PEA2; PEA2 beta; PEA2beta; PEBB_HUMAN; PEBP
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CBFb/PEB
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位:细胞核
多瘤病毒增强了结合蛋白2β抗体产品介绍:background: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. Function: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. Subunit: Heterodimer with RUNX1. Subcellular Location: Nucleus. DISEASE: Note=A chromosomal aberration involving CBFB多瘤病毒增强了结合蛋白2β抗体 is associated with acute myeloid leukemia of M4EO subtype. Pericentric inversion inv(16)(p13;q22). The inversion produces a fusion protein that consists of the 165 N-terminal residues of CBF-beta (PEPB2) with the tail region of MYH11. Similarity: Belongs to the CBF-beta family. Database links: UniProtKB/Swiss-Prot: Q13951.2 Important Note: This product as supplied is intended for 多瘤病毒增强了结合蛋白2β抗体research use only, not for use in human, therapeutic or diagnostic applications.
产多瘤病毒增强了结合蛋白2β抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid