热休克蛋白27相关蛋白1抗体
规格:1mg/1ml
英文名: HSPBAP1
别名: 27 KdA heat shock protein-associated protein 1; HBAP1_HUMAN; hspbap; HSPB1-associated protein 1; HSPBAP1; PASS1; Protein associated with small stress protein 1; protein associating with small stress p
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSPBAP1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
热休克蛋白27相关蛋白1抗体细胞定位:细胞浆
产品介绍:background: Heat Shock Protein BAP1 (heat shock 27-kDa-associated protein 1, or HSPBAP1) inhibits the function of heat shock protein 27, which has a neuroprotective effect during experimentally induced epileptic neuropathology. The HSPBAP1 protein, also known as PASS1, contains a jmjC motif, suggesting it is a member of the jumonji family of transcription factors. There is evidence of domain swapping within the jumonji family genes, and the HSPBAP1 gene has been shown to fuse with a novel gene called DIRC3 in hereditary热休克蛋白27相关蛋白1抗体 renal cell cancer. Function: May play a role in cellular stress response. Subunit: Interacts with CRYAB and HSPB1. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. DISEASE: Note=A chromosomal aberration involving HSPBAP1 has热休克蛋白27相关蛋白1抗体 been found in a family with renal carcinoma. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids. Similarity: Contains 1 JmjC domain. Database links: UniProtKB/Swiss-Prot: Q96EW2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产热休克蛋白27相关蛋白1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid