锌指蛋白Zdhhc12抗体
规格:1mg/1ml
英文名: ZDHHC-12
别名: DHHC12; DHHC-12; Palmitoyltransferase ZDHHC12; ZDH12_HUMAN; Zdhhc12; Zinc finger DHHC domain-containing protein 12; DHHC-12; Probable palmitoyltransferase ZDHHC12; ZDH12_HUMAN; ZDHHC12; Zinc finger DH
分子量: 30kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZDHHC-12
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞膜
锌指蛋白Zdhhc12抗体产品介绍:background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC12 (zinc finger, DHHC domain containing 12), also known as ZNF400, is a 267 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to a S-palmitoyl protein and free CoA. Three isoforms exist due to alternative splicing events. The gene encoding ZDHHC12 maps to human chromosome 9, which consists of锌指蛋白Zdhhc12抗体 about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Subcellular Location: Membrane; Multi-pass membrane protein Similarity: Belongs to the DHHC palmitoyltransferase family. Contains 1 DHHC-type zinc finger. Database links: Entrez Gene: 505354 Cow Entrez Gene: 608478 Dog Entrez Gene: 100066906 Horse锌指蛋白Zdhhc12抗体 Entrez Gene: 84885 Human Entrez Gene: 100519816 Pig Entrez Gene: 366014 Rat SwissProt: Q96GR4 Human SwissProt: Q6DGF5 Rat Unigene: 133122 Human Unigene: 95138 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白Zdhhc12抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转录调节因子 锌指蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid