叉头蛋白N1抗体
规格:1mg/1ml
英文名: FOXN1
别名: FKHL20; Forkhead box N1; Forkhead box protein N1; FOXN 1; FOXN1; FOXN1_HUMAN; RONU; Rowett nude; Transcription factor winged-helix nude; WHN; Winged helix nude; Winged-helix transcription factor nude.
分子量: 69kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FOXN1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
叉头蛋白N1抗体产品介绍:background: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative 叉头蛋白N1抗体splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008]. Function: Transcriptional regulator involved in development. Subcellular Location: Nucleus. Tissue Specificity: Expressed in thymus. Similarity: Contains 1 fork-head DNA-binding 叉头蛋白N1抗体omain. Database links: UniProtKB/Swiss-Prot: O15353.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产叉头蛋白N1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 染色质和核信号 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid