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乙型肝炎病毒X蛋白相互作用蛋白

乙型肝炎病毒X蛋白相互作用蛋白
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  • 产品名称:乙型肝炎病毒X蛋白相互作用蛋白
  • 产品型号:HBXIP
  • 产品展商:单克隆抗体/多克隆抗体
  • 产品文档:无相关文档
简单介绍
乙型肝炎病毒X蛋白相互作用蛋白应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。乙型肝炎病毒X蛋白相互作用蛋白生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品描述

乙型肝炎病毒X蛋白相互作用蛋白

规格:1mg/1ml

英文名: HBXIP

别名: HBV X interacting protein; HBX interacting protein; Hepatitis B virus X interacting protein; MGC71071; XIP; HBXIP_HUMAN.

分子量: 9.6kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human HBXIP (5

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

细胞定位:细胞浆

乙型肝炎病毒X蛋白相互作用蛋白产品介绍:background: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Function: When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. Subunit: Homodimer (Probable). Interacts with phosphorylated BIRC5; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently. Interacts with SUPV3L1. Interacts with hepatitis B virus (HBV) oncoprotein HBX 乙型肝炎病毒X蛋白相互作用蛋白C-terminus. Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection. Post-translational modifications: Phosphorylated upon DNA damage乙型肝炎病毒X蛋白相互作用蛋白, probably by ATM or ATR. Similarity: Belongs to the HBXIP family. Database links: Entrez Gene: 10542 Human Entrez Gene: 68576 Mouse Entrez Gene: 295357 Rat Omim: 608521 Human SwissProt: O43504 Human SwissProt: Q9D1L9 Mouse Unigene: 439815 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

乙型肝炎病毒X蛋白相互作用蛋白产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  **学  细胞凋亡  **及病毒  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid




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