环指蛋白189抗体
规格：1mg/1ml
英文名： RING finger protein 189
别名： CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rififylin; E3 ubiquitin-pro
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RING fin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
环指蛋白189抗体产品介绍：background: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates. Subunit: Binds CASP8 and CASP10. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications: Rapidly degraded after stimulation with TNFSF10, probably by caspases. Auto-ubiquitinated (in vitro). Palmitoylated. Similarity: Contains 1 FYVE-type zinc finger. Contains 环指蛋白189抗体1 RING-type zinc finger. Contains 2 SAP domains. Gene ID: 117584 Database links: Entrez Gene: 530263 Cow Entrez Gene: 117584 Human Entrez Gene: 67338 Mouse Entrez Gene: 282844 Rat Omim: 609735 Human SwissProt: Q8WZ73 Human SwissProt: Q6ZQM0 环指蛋白189抗体Mouse SwissProt: Q8CIN9 Rat Unigene: 13680 Human Unigene: 341608 Mouse Unigene: 159718 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产环指蛋白189抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid