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环指蛋白189抗体

环指蛋白189抗体
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  • 产品名称:环指蛋白189抗体
  • 产品型号: RING finger protein 189
  • 产品展商:单克隆抗体/多克隆抗体
  • 产品文档:无相关文档
简单介绍
环指蛋白189抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。环指蛋白189抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品描述

环指蛋白189抗体

规格:1mg/1ml

英文名: RING finger protein 189

别名: CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rififylin; E3 ubiquitin-pro

分子量: 40kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human RING fin

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

细胞定位:细胞浆 细胞膜

环指蛋白189抗体产品介绍:background: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates. Subunit: Binds CASP8 and CASP10. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications: Rapidly degraded after stimulation with TNFSF10, probably by caspases. Auto-ubiquitinated (in vitro). Palmitoylated. Similarity: Contains 1 FYVE-type zinc finger. Contains 环指蛋白189抗体1 RING-type zinc finger. Contains 2 SAP domains. Gene ID: 117584 Database links: Entrez Gene: 530263 Cow Entrez Gene: 117584 Human Entrez Gene: 67338 Mouse Entrez Gene: 282844 Rat Omim: 609735 Human SwissProt: Q8WZ73 Human SwissProt: Q6ZQM0 环指蛋白189抗体Mouse SwissProt: Q8CIN9 Rat Unigene: 13680 Human Unigene: 341608 Mouse Unigene: 159718 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

环指蛋白189抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  信号转导  细胞凋亡  转录调节因子  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid




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