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核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体

核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体
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  • 产品名称:核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体
  • 产品型号:Nucleostemin
  • 产品展商:单克隆抗体/多克隆抗体
  • 产品文档:无相关文档
简单介绍
核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品描述

核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体

规格:1mg/1ml


英文名: Nucleostemin

别名: E2 induced gene 3 protein; E2IG3; Estradiol induced nucleotide binding protein; GNL3; Guanine nucleotide binding protein like 3 (nucleolar); Guanine nucleotide binding protein like 3; MGC800; NNP47; N

分子量: 62kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human Nucleost

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,

细胞定位:细胞核

核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产品介绍:background: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, ***** CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most ***** tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells. Function: May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. Subunit: Interacts with MDM2; this interaction stabilizes MDM2. Interaction with MDM2 occurs in the nucleoplasm and is triggered by a nucleolar release mechanism, such as mitosis-induced nucleolar disassembly (By similarity). Indirectly interacts with TP53, via MDM2-binding (By similarity). Subcellular Location: Nucleus. Nucleus. nucleolus. 核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体Shuttles between the nucleus and nucleolus. Tissue Specificity: Increased levels in lung tissue in cancer patients. Similarity: Belongs to the MMR1/HSR1 GTP-binding protein family. Contains 1 G (guanine nucleotide-binding) domain. Gene ID:核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体 26354 Database links: Entrez Gene: 26354 Human Entrez Gene: 30877 Mouse Entrez Gene: 290556 Rat Omim: 608011 Human SwissProt: Q9BVP2 Human SwissProt: Q8CI11 Mouse SwissProt: Q811S9 Rat Unigene: 313544 Human Unigene: 88512 Mouse Unigene: 4110 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  神经生物学  干细胞  细胞类型标志物  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid





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