半胱胺酸蛋白酶蛋白5抗体
规格：1mg/1ml
英文名： Caspase 5
别名： Caspase-5 subunit p20; Apoptosis related cysteine protease; CASP 5; CASP5; Caspase-5; Caspase5; Caspase 5 apoptosis related cysteine peptidase; caspase 5 apoptosis related cysteine protease; ICE; ICE(
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Caspase
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
半胱胺酸蛋白酶蛋白5抗体产品介绍：background: Caspase 5 belongs to the Ced3/ICE family of cystein proteases and is an upstream Caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have high homology with several other Caspases over the equivalent coding sequences. Subunit: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10kDa (p10) subunits. Tissue Specificity: Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle. Similarity: Belongs to the peptidase C14A family. Contains 1 CARD 半胱胺酸蛋白酶蛋白5抗体domain. Gene ID: 838 Database links: Entrez Gene: 838 Human Omim: 602665 Human SwissProt: 半胱胺酸蛋白酶蛋白5抗体P51878 Human Unigene: 213327 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. caspase-5与ICE有51%的同源性，并具有保守的活性中心QACRG。但caspase-5不能剪切pro-IL-1b ，在过量表达时可以诱导凋亡的发生。此抗体与caspase 4 同源。
半胱胺酸蛋白酶蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid