前列腺素E受体4相关蛋白抗体
规格:1mg/1ml
英文名: FEM1A
别名: EPRAP; Fem-1 homolog a (C. elegans); Fem1 homolog a; FEM1-alpha-A; FEM1a-A; Fem1aa; Feminization 1 homolog a (C. elegans); Feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Prot
分子量: 74kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FEM1A
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
前列腺素E受体4相关蛋白抗体产品介绍:background: FEM1A is a caspase substrate homologous to the C. Elegans sex determining protein, FEM-1. Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Overexpression of FEM1A in mammalian cells is reported to induce apoptosis. Function: Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Subunit: Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4. Subcellular Location: Cytoplasm (Probable). Tissue Specificity: Present in macrophages derived from peripheral blood monocytes. Also present in 前列腺素E受体4相关蛋白抗体atheromata (at protein level). Similarity: Belongs to the fem-1 family. Contains 9 ANK repeats. Contains 2 TPR repeats. Gene ID: 55527 Database links: Entrez Gene: 516550 Cow Entrez Gene: 55527 Human Entrez Gene: 14154 Mouse Entrez Gene: 前列腺素E受体4相关蛋白抗体316131 Rat GenBank: NP_061178.1 Human SwissProt: Q29RM5 Cow SwissProt: Q9BSK4 Human SwissProt: Q8C4V3 Mouse SwissProt: Q4V890 Rat Unigene: 515082 Human Unigene: 290813 Mouse Unigene: 228392 Rat Unigene: 97265 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列腺素E受体4相关蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid