分化相关基因2蛋白/立即早期反应蛋白抗体
规格:1mg/1ml
英文名: IEX1
别名: IEX1; PRG1; Anti death protein; Differentiation dependent gene 2 protein; DIF 2; DIF2; Differentiation dependent gene 2; Differentiation dependent gene 2 protein; Differentiation-dependent gene 2 prot
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IEX1/Dif
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
分化相关基因2蛋白/立即早期反应蛋白抗体产品介绍:background: This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008]. Function: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. Subunit: Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.分化相关基因2蛋白/立即早期反应蛋白抗体 Subcellular Location: Membrane; Single-pass type II membrane protein. Post-translational modifications: Glycosylated. Similarity: Belongs to the IER3 family. Gene ID: 8870 Database links: Entrez Gene: 8870 Human Entrez分化相关基因2蛋白/立即早期反应蛋白抗体 Gene: 15937 Mouse Omim: 602996 Human SwissProt: P46695 Human SwissProt: P46694 Mouse Unigene: 730861 Human Unigene: 76095 Human Unigene: 25613 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
分化相关基因2蛋白/立即早期反应蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 信号转导 干细胞 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid