Prohibitin抗体

Prohibitin抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

1、全：网络全世界的上等产品，基本上各种抗体产品在该公司均能找到

2、新：产品及网站更新非常快，基本上每周均有新产品出现

3、优：产品质量好，投诉比较少

4、强：强大的技术支持队伍和力量，网站上有齐全的技术资料以及客户评论，并提供实时在线技术咨询，使您使用产品时没有任何后顾之忧。

产品编号xy-1449R

英文名称Prohibitin

中文名称抑制素/肿瘤抑制因子抗体

别    名Mitochondrial Marker; PHB; prohibitin; PHB1; Prohibitin - Mitochondrial Marker; PHB_HUMAN.  

JournalPMIDIFApplicationEnvironmental Toxicology and Pharmacology (2015)263563892.0840WB

说 明 书50ul  100ul  200ul

研究领域肿瘤  细胞生物  染色质和核信号  细胞凋亡  细胞类型标志物  

抗体来源Rabbit

克隆类型Polyclonal

Prohibitin抗体交叉反应 Human, Mouse, Rat, Dog, Horse,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量30kDa

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human Prohibitin

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

Subunit:

Interacts with PHB2. Interacts with STOML2.

Subcellular Location:

Mitochondrion inner membrane.

Tissue Specificity:

Widely expressed in different tissues.

Similarity:

Belongs to the prohibitin family.

SWISS:

P35232

Gene ID:

5245