TAG1抗体

TAG1抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产品具有以下特点:

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产品编号xy-5845R

英文名称TAG1

中文名称瞬时表达轴索糖蛋白1抗体

别    名Axonal glycoprotein TAG 1; Axonal glycoprotein TAG-1; Axonal glycoprotein TAG1; Axonin 1; Axonin-1; Axonin1; AXT; CNTN 2; Cntn2; CNTN2_HUMAN; contactin 2 (axonal); Contactin 2; Contactin-2; Contactin2; DKFZp781D102; MGC157722; TAG 1; TAG 564; TAG564; TAX 1; TAX; TAX-1; TAX1; Transient axonal glycoprotein 1; Transiently expressed axonal glycoprotein.  

说 明 书100ul  200ul

研究领域肿瘤  **学  神经生物学  生长因子和**  细胞粘附分子  细胞外基质  

抗体来源Rabbit

克隆类型Polyclonal

TAG1抗体交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量107kDa

细胞定位细胞膜

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human TAG1

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产品介绍background:

Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.

Function:

May play a role in the initial growth and guidance of axons. May be involved in cell adhesion.

Subcellular Location:

Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.

Similarity:

Belongs to the immunoglobulin superfamily. Contactin family.

Contains 4 fibronectin type-III domains.

Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:

Q02246

Gene ID:

6900